Mechanical Stimulation of Stem Cells Using Cyclic Uniaxial Strain
نویسندگان
چکیده
منابع مشابه
Nanoscale Mechanical Stimulation of Human Mesenchymal Stem Cells
Introduction: Mechanical stimulation of human mesenchymal stem cells has demonstrated changes in many cell behaviours such as adhesion, migration, growth and differentiation through mechanotransductive pathways. These include experiments on effect of nanotopography 1, shear stress, stiffness of extracellular matrix 2, strain, stress and acoustic wave energy 3 on cells. In this research we wer...
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Tissue engineering skeletal muscle in vitro is of great importance for the production of tissue-like constructs for treating tissue loss due to traumatic injury or surgery. However, it is essential to find new sources of cells for muscle engineering as efficient in vitro expansion and culture of primary myoblasts are problematic. Mesenchymal stem cells may be a promising source of myogenic prog...
متن کاملnanoscale mechanical stimulation of human mesenchymal stem cells
introduction: mechanical stimulation of human mesenchymal stem cells has demonstrated changes in many cell behaviours such as adhesion, migration, growth and differentiation through mechanotransductive pathways. these include experiments on effect of nanotopography 1, shear stress, stiffness of extracellular matrix 2, strain, stress and acoustic wave energy 3 on cells. in this research we were ...
متن کاملcomparison of osteogenic medium and uniaxial strain on differentiation of endometrial stem cells
background: mechanotransduction plays a pivotal role in remodeling and repair of skeletal tissues. this mechanism has been widely used in bone tissue engineering especially under in vitro conditions. to date, various stem cells have been used for this purpose. the present study was thefirst to evaluate the effect of mechanical loading on differentiation of human endometrial stemcells (hescs) to...
متن کاملUniaxial Mechanical Strain Modulates the Differentiation of Neural Crest Stem Cells into Smooth Muscle Lineage on Micropatterned Surfaces
Neural crest stem cells (NCSCs) play an important role in the development and represent a valuable cell source for tissue engineering. However, how mechanical factors in vivo regulate NCSC differentiation is not understood. Here NCSCs were derived from induced pluripotent stem cells and used as a model to determine whether vascular mechanical strain modulates the differentiation of NCSCs into s...
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2007
ISSN: 1940-087X
DOI: 10.3791/242